Endocrine Abstracts

Background: Radiofrequency ablation has been advocated as an alternative to radioiodine and/or surgery for the treatment of autonomously functioning benign thyroid nodules. However, only a few studies have measured radiofrequency ablation efficacy on autonomously functioning benign thyroid nodules. The aim of this work was to evaluate the 24-month efficacy of a single session of radiofrequency ablation (performed with the moving shot technique) on solitary autonomously functio...

Introduction: Shift work has been associated with increased cardiovascular morbidity and mortality. Several studies have demonstrated that shift work has an effect on cardiovascular and metabolic health. Most of these studies have compared different groups of shift workers to nonshift workers. By contrast, the present work aimed to evaluate the cardio-metabolic effects of night shifts on the same group of internists as they changed type of duty. In particular, we focused on bl...

Familial pituitary adenoma is frequently associated with germinal mutations of several genes, including menin gene. MEN1 syndrome is an autosomic dominant disease, characterized by parathyroid adenomas, endocrine gastroenteropancreatic tumors, and pituitary adenomas, due to inactivating mutations of the MenI gene (11q13). MEN1 mutations are scattered within and around the menin open reading frame and are mainly represented by single nucleotide polymorphisms (SNPs), and ...